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The most widely used blood test for liver cancer is a test for alpha-fetoprotein (AFP), which is a protein normally made by the liver cells in a fetus. Infants have high levels of AFP which generally fall to normal adult levels in the first year of life. In pregnant women high levels of AFP may indicate congenital problems with the baby.
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The most important application of AFP testing in cancer management is for testicular cancer. The measurement of AFP in serum, in conjunction with serum hCG, is an established regimen for monitoring patients with nonseminomatous testicular cancer. In addition, monitoring the rate of AFP clearance from serum after treatment is an indicator of the effectiveness of therapy. Conversely, the growth rate of progressive cancer can be monitored by serially measuring serum AFP concentration over time.
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Principle of the test: The AFP ELISA test is based on the principle of a solid phase enzyme-linked immunosorbent assay. The assay system utilizes a rabbit anti-AFP antibody directed against intact AFP for solid phase immobilization (on the microtiter wells). A monoclonal anti-AFP antibody conjugated to horseradish peroxidase (HRP) is in the antibody-enzyme conjugate solution. The test sample is allowed to react first with the immobilized rabbit antibody for 30 minutes. The wells are washed to remove...
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alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (1B10) Related Products
If you are experiencing difficulties placing your order, please contact our order department for assistance at 1-800-833-8651 or 1-734-668-6113.
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This digital document is an article from Family Practice News, published by Thomson Gale on April 1, 2006. The length of the article is 466 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: AFP testing deemed expensive, obsolete.(Women's Health)(alpha fetoprotein) Author: Damian McNamara Publication:...
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Also known as: AFP Quad Screen. This test includes: Alpha-fetoprotein, serum; Dimeric Inhibin A (DIA); Human Chorionic Gonadotropin (hCG); Unconjugated Estriol (uE3). AFP tetra is a screening test. A positive AFP tetra result means that more diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present. Note: This test requires some additional information in order to complete the requisition. When you are ready to place your...
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Host: mouse monoclonal; Species Reactivity: human, dog, pig; Does not react with cow, cat, mouse, and rat.; Application: IHC-P
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This digital document is an article from OB GYN News, published by Thomson Gale on September 1, 2005. The length of the article is 474 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Adding ultrasound ups sensitivity of AFP screen to 98%: study.(alpha fetoprotein ) Author: Jerry Ingram Publication:...
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Also known as: AFP X-tra, Triple Test. This test includes: ?-Fetoprotein (AFP); human chorionic gonadotropin (hCG); unconjugated estriol (uE3) levels in serum. This is used as a screening test for open neural tube defects, Down syndrome and trisomy 18. A positive AFP X-tra result means that more diagnostic testing may be offered to the pregnant woman to determine if neural tube defect or chromosome abnormality is present.
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Antibodies-Mouse Anti-human Alpha fetoprotein (AFP) (clone 1)-Alpha
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This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome...
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AFP is a major plasma protein produced by the yolk sac and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
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alpha-Fetoprotein (AFP) Monoclonal Antibody (3B10)
AFP is a major plasma protein produced by the yolk sac and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
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The AFP-L3% test is intended for use in the assessment of risk for the development of hepatocellular carcinoma (HCC) in patients with chronic liver diseases. A significant deviation from the normal range may require further evaluation by your physician.
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PY-10264 - Anti-alpha-1-fetoprotein (AFP),Chicken-Polyclonal
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alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (10B8) 1 mg HYB 097-04-1 $4,405.00
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Important Notes: During shipment, small volumes of AFP antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
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alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (6F4)
alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (6F4) 50 µg HYB 097-08-S $320.00
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AFP is a major plasma protein produced by the yolk sac and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
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alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (1F6) 200 µL HYB 097-07-02 $970.00
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alpha-Fetoprotein (AFP) (human) Monoclonal Antibody (7C6) 200 µg HYB 097-09-02 $970.00
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AFP is a major plasma protein produced by the yolk sac and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
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alpha-Fetoprotein (AFP) Monoclonal Antibody (4D11)
AFP is a major plasma protein produced by the yolk sac and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
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Antibodies-Mouse Anti-human Alpha fetoprotein (AFP) (clone 2)-Alpha
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Alpha-Fetoprotein (AFP), Maternal Serum for Open Spina Bifida
Also know as: AFP, Maternal Serum, maternal Serum Alpha-Fetoprotein, msAFP
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(US)
